MR imaging and MR spectroscopy in rhizomelic chondrodysplasia punctata.
نویسندگان
چکیده
A case of rhizomelic chondrodysplasia punctata was investigated with MR imaging of the brain and hydrogen-1 MR spectroscopy of the brain and blood. Areas with abnormal signal hyperintensity on T2-weighted images or hypointensity on T1-weighted images were detected in the subcortical white matter. MR spectroscopy of the brain showed that normal-appearing white matter was characterized by increased levels of mobile lipids and myo-inositol, reduced levels of choline, and the presence of acetate. The importance of these metabolic anomalies is correlated to the deficiency in plasmalogen biosynthesis.
منابع مشابه
Cranial MR imaging in rhizomelic chondrodysplasia punctata.
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ورودعنوان ژورنال:
- AJNR. American journal of neuroradiology
دوره 23 3 شماره
صفحات -
تاریخ انتشار 2002